Abstract

The danger inherent in formulating specific models to explain physicsl- biological phenomena is discussed. Some of the phenomenological observations on effects of ionizing radiations on cell division in yeast are reviewed. Recent observations made on the modification of radiation damage in yeast by various envirommental agents are described. These findings are analyzed within the frameworks of the generalized migration model of Zirkle and Tobias and of the modified directaction model formulated by Alper, Howard-Flanders, Alexander, and others. 34 references. (C.H.)

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