Inhibition of Candida Fungi and E. Coli Bacteria in Zein Nanoparticles Conjugated with Silver ion (Ag0+)

Abstract

The theme of the present research was to investigate the capacity of zein nanopartic*les conjugated with silver ions (Ag0+) in the inhibition of both E. coli and Candida albicans development. Both Escherichia coli (knownas E. coli) and Candida albicans are widely speared not only in human body and found in various subtypes in human pathology. E. coli (a large group of diverse bacteria) is found everywhere in the environment, foods, and intestines of people and animals. A similar presence has also the fungi Candida albicans in the human body. Its occurrence is normal but in certain conditions the speed and capacity of multiplication can lead diseases manly in organisms with low immunity systems. From long time in history, silver is recognized as antimicrobial agent and in the recent times, silver nanoparticles have been demonstrated to be both antifungal and antibacterial agent1. Besides there is the potential of zein nanoparticles in the process of nanoencapsulation in different composite patterns (gold(Au), silver (Ag), cobalt ferrite (CoFe), iron (III), pyrophosphate (FePPi), magnetite (mag), and many others) were tested over the time and the results were promising for future enhancements of the methods with wide practical uses