Abstract
Objective: Fallopian tube carcinoma (FTC) had a higher reported frequency of inherited BRCA mutations than ovarian carcinoma (OC) or primary peritoneal carcinoma (PPC). We hypothesized that the adoption of serial sectioning of the fallopian tube would lead to an increased proportion of cases designated as FTC and could change mutation fraction. We investigated the prevalence of inherited mutations in women with FTC compared with OC and PPC, and how the fraction of FTC and inherited mutations changed over time.
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