Abstract
Rats were given single or multiple (10 exposures at about 21-d intervals) inhalation exposures to 244CmO2 starting at 70 d of age. Mean lung and bone doses (+/- standard deviation) were 1.4 +/- 1.3 and 0.74 +/- 1.1 Gy, respectively, in the single exposure group, and 1.8 +/- 2.9 and 0.53 +/- 0.74 Gy, respectively, in the multiple exposure group. After cessation of exposure in the multiple exposure group, mean cumulative lifetime radiation doses to lung and skeleton were not significantly different in the two groups. The percentages of rats with lung and bone tumors were 9.1 and 12%, respectively, in the single exposure group, and 20 and 24%, respectively, in the multiple exposure group. However, the multiple exposure regimen did not significantly alter survival times or tumor incidences in lung or bone from a single inhalation exposure to 244CmO2 when survival patterns were taken into account.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
