Abstract
Abstract 1. 1. Statistics are presented of reactions of 350 guinea pigs sensitized and shocked by inhalation of horse dander in various controlled weather conditions. More than 1,500 shock exposures were made. 2. 2. The conditions under which the greatest number and most severe anaphylactic reactions occurred were: (a) shifting from hot dry air to low barometric pressure, (b) shifting from low pressure to hot dry air, and (c) shifting from hot moist to cold dry air without the allergen and back to hot moist with the allergen. 3. 3. The single weather conditions, in the order of the number of severe reactions which occurred in each were: (a) hot dry, (b) room air, (c) cold dry, (d) hot moist, and (e) cold moist air. 4. 4. The single weather conditions, in the order in which the greatest number of all types of reactions occurred were: (a) hot moist, (b) cold dry, (c) hot dry, (d) room air, and (e) cold moist air. 5. 5. The single weather conditions, in the order in which the most severe reactions in the first shock exposure occurred were: (a) hot dry, (b) hot moist, (c) cold dry, (d) room air, and (e) cold moist air. 6. 6. In one well controlled experiment the experimental low pressure condition was conducive to a significantly higher number of reactions than was that of high pressure.
Published Version
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