Abstract
Fourier Transform Infrared Microscopy enables to study small samples by means of high quality spectra. Biochemical and morphological changes in carotid plaques and thyroid tissues have been displayed by drawing three-dimensional chemical maps of the main vibrational modes in regions of interest. A huge number of spectra were collected that allow to point out even subtle changes in the main components. Micro FT-IR spectroscopy is suited for in vivo clinical diagnostics, immunocytochemical analysis and ex vivo histological determinations to establish a suitable protocol for the study of lesions in human tissues, even at an early stage.
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