Abstract
Different implant materials are currently applied for correction of inborn and acquired aesthetic deficiencies of the human skin. Several commercial products are used as dermal fillers for aesthetic facial surgery, which contain bovine collagen and cross-linked substances, or hyaluronic acid derivatives, both also in combination with polymethylmethacrylate or co-polymerisates of methacrylate derivatives. Gels containing polylactate or dimethylpolysiloxane were also available. Infrared spectra of such products are presented after dry film preparation. Infrared microscopy using attenuated total reflection was employed to identify previously applied dermal filler products in excised tissue without embedding the sample in a matrix material such as paraffin as needed for microtoming. Several tissue spots guided by inspecting the different color grades were found with increased single implant component concentrations, as supported by the dominating spectral features and difference spectroscopy. The chemistry within dermal biopsies after material implantation can be uniquely investigated based on their infrared spectra.
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