Abstract
IntroductionSpectral-domain optical coherence tomography findings in a patient with acute macular neuroretinopathy, and correlation with functional defects on microperimetry, are presented.Case presentationA 25-year old Caucasian woman presented with bitemporal field defects following an upper respiratory tract infection. Her visual acuity was 20/20 in both eyes and a dilated fundus examination revealed bilateral hyperpigmentary changes in the papillomacular bundle. Our patient underwent further evaluation with spectral-domain optical coherence tomography, infrared and fundus autofluorescence imaging. Functional changes were assessed by microperimetry. Infrared imaging showed the classic wedge-shaped defects and spectral-domain optical coherence tomography exhibited changes at the inner segment-outer segment junction, with a thickened outer plexiform layer overlying these areas. Fluorescein and indocyanine green angiography did not demonstrate any perfusion defects or any other abnormality. Microperimetry demonstrated focal elevation in threshold correlating with the wedge-shaped defects in both eyes.ConclusionSpectral-domain optical coherence tomography findings provide new evidence of the involvement of the outer plexiform layer of the retina in acute macular neuroretinopathy.
Highlights
Spectral-domain optical coherence tomography findings in a patient with acute macular neuroretinopathy, and correlation with functional defects on microperimetry, are presented.Case presentation: A 25-year old Caucasian woman presented with bitemporal field defects following an upper respiratory tract infection
Findings on time domain optical coherence tomography (OCT) indicate that the pathology is located in the outer retina [3]
We present findings of infrared (IR) imaging and spectral-domain OCT (SD-OCT; Spectralis, Heidelberg, Germany) and correlate these with retinal function by
Summary
Spectral-domain optical coherence tomography findings in a patient with acute macular neuroretinopathy, and correlation with functional defects on microperimetry, are presented.Case presentation: A 25-year old Caucasian woman presented with bitemporal field defects following an upper respiratory tract infection. Conclusion: Spectral-domain optical coherence tomography findings provide new evidence of the involvement of the outer plexiform layer of the retina in acute macular neuroretinopathy. Introduction Acute macular neuroretinopathy (AMNR) is a rare condition characterized by wedge-shaped lesions pointing towards the foveal center, resulting in bilateral or unilateral scotomas, typically with preserved central visual acuities [1,2]. The association of this condition with oral contraceptive (OCP) use and intravenous sympathomimetic administration suggests a vascular etiology, angiography has consistently failed to demonstrate a perfusion defect [2].
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