Abstract

A 22-year-old newly diagnosed patient with bipolar is discussing with her doctor the safety of starting an atypical antipsychotic as part of her treatment plan for depression. The patient was recently diagnosed with bipolar disorder after years of ups and downs making school and her relationship especially difficult. After seeking out a university student health psychiatrist for a severe depressive episode she was prescribed an antidepressant, which within a few weeks triggered a manic episode that required hospitalization. Since that time she has been compliant with her medications but has fallen into another depressive episode. Her psychiatrist encourages her to begin taking the atypical antipsychotic quetiapine because it may help with her current mood. Given her experience with antidepressants she is apprehensive. She asks, is it possible that a medication like quetiapine could trigger another manic episode?

Highlights

  • Clarisse Taylor, a 22-year-old patient with newly diagnosed bipolar I disorder is asking her doctor about the safety of starting an atypical antipsychotic as part of her treatment plan for depression

  • These experiences were disruptive to her life and affected trust in the doctors she needed to help manage her disorder. She has been adherent with her medications but has experienced another depressive episode. Her psychiatrist encourages her to begin taking the atypical antipsychotic quetiapine because it may help with her current mood

  • In order to address the patient’s concerns, an investigation of the ability of antipsychotics to induce mania in bipolar patients was performed in the literature

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Summary

Medical Research Commons

Informed Consent: Do atypical antipsychotics trigger manic switching in patients with bipolar I disorder? This Informed Consent is brought to you for free and open access by the Open Access Journals at DigitalCommons@WayneState. It has been accepted for inclusion in Clinical Research in Practice: The Journal of Team Hippocrates by an authorized editor of DigitalCommons@WayneState

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