Abstract

BackgroundOntologies are widely used both in the life sciences and in the management of public and private companies. Typically, the different offices in an organization develop their own models and related ontologies to capture specific tasks and goals. Although there might be an overall coordination, the use of distinct ontologies can jeopardize the integration of data across the organization since data sharing and reusability are sensitive to modeling choices.ResultsThe paper provides a study of the entities that are typically found at the reception, analysis and report phases in public institutes in the life science domain. Ontological considerations and techniques are introduced and their implementation exemplified by studying the Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), a public veterinarian institute with different geographical locations and several laboratories. Different modeling issues are discussed like the identification and characterization of the main entities in these phases; the classification of the (types of) data; the clarification of the contexts and the roles of the involved entities. The study is based on a foundational ontology and shows how it can be extended to a comprehensive and coherent framework comprising the different institute’s roles, processes and data. In particular, it shows how to use notions lying at the borderline between ontology and applications, like that of knowledge object. The paper aims to help the modeler to understand the core viewpoint of the organization and to improve data transparency.ConclusionsThe study shows that the entities at play can be analyzed within a single ontological perspective allowing us to isolate a single ontological framework for the whole organization. This facilitates the development of coherent representations of the entities and related data, and fosters the use of integrated software for data management and reasoning across the company.

Highlights

  • Ontologies are widely used both in the life sciences and in the management of public and private companies

  • When described in terms of lexical semantics, ontologies take the simple form of dictionaries or thesauri; when described in terms of axioms in a logical language, we talk about formal ontologies; if logical constraints are encoded in a computational language, formal ontologies turn into computational ontologies

  • We showed how to perform an ontological analysis of the domain, what distinctions it highlights, and how to model them in an ontology

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Summary

Introduction

Ontologies are widely used both in the life sciences and in the management of public and private companies. Ontological techniques are applied towards a variety of goals [9] among which the study and organization of areas like genomics [10], anatomy [11, 12], plant anatomical and morphological structures [13], phenotype annotation [14], with important results in knowledge modeling, organization, integration and exploitation [8, 15, 16]. Notwithstanding these achievements, the application of ontological techniques is still problematic [17]

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