Abstract
Address: 1Department of Computer Science, Tehran University, Tehran, Iran, 2Biophysics Program, University of Wisconsin-Madison, Madison, WI 53706, USA, 3Department of Psychiatry, Duke University & Medical Center, Durham, NC 27710, USA, 4Department of Anesthesiology, Duke University & Medical Center, Durham, NC 27710, USA, 5Department of Research Partnering, Roche Palo Alto LLC, CA 94304, USA and 6Department of Mathematics, University of Wisconsin-Madison, Madison, WI 53706, USA
Highlights
Sixteenth Annual Computational Neuroscience Meeting: CNS*2007 William R Holmes Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here http://www.biomedcentral.com/content/pdf/1471-2202-8-S2-info.pdf
This paper reports progress in construction of a new network structure, called the InfoMax Gene Network, for exploring genome-scale inter-relationships among families of genes in order to specify pathways activated during the experiments that perturb a control system
In the empirical topology approach to systems biology, the set of genes is endowed with a certain geometric structure, so that a genomic space is constructed according to representations of systemslevel information carried by the gene expression data, as 'perturbed signals' carry information regarding the noise or other factors underlying the perturbation relative to the control group
Summary
InfoMax gene networks constructed from intervention in the animal models of Parkinson's disease. Hesam T Dashti[1], Mary Kloc*2, Tong Lee[3], Gregory Michelotti[4], Tingting Zhang[5] and Amir Assadi[6]. Address: 1Department of Computer Science, Tehran University, Tehran, Iran, 2Biophysics Program, University of Wisconsin-Madison, Madison, WI 53706, USA, 3Department of Psychiatry, Duke University & Medical Center, Durham, NC 27710, USA, 4Department of Anesthesiology, Duke University & Medical Center, Durham, NC 27710, USA, 5Department of Research Partnering, Roche Palo Alto LLC, CA 94304, USA and 6Department of Mathematics, University of Wisconsin-Madison, Madison, WI 53706, USA. Sixteenth Annual Computational Neuroscience Meeting: CNS*2007 William R Holmes Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here http://www.biomedcentral.com/content/pdf/1471-2202-8-S2-info.pdf
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