Abstract
During 13 years, 190 individuals with chagasic infection were submitted to clinical and parasitological examinations to investigate the relationship between parasitemia and the evolution of chronic chagasic infection. Fifty-six patients with positive xenodiagnosis and 134 with negative exams were compared from 1988 to 91, it was found that 22 (39.3%) and 50 (37.3%), respectively, presented disease progression. The parasitemia was stratified into high, medium and low and the relation with the disease evolution showed that 5 (62.5%), 10 (41.7%) and 57 (36.1%), respectively, presented progressive disease, though without a statistically significant difference (p>0.05). When 20 patients with persistent parasitemia in 1976/91, were compared with 59 with negative xenodiagnosis, a progressive evolution was observed in 6 (30%) and 17 (28.8%), respectively. Comparing six patients with high parasitemia and 59 with negative exams, it was verified that 3 (50%) and 17 (28.8%), respectively, showed progressive disease, but this was not statistically significant, (p>0.05). Mean age with high, medium and low parasitemia were 39.6, 45.3 and 41.5 years, respectively, (p>0.05). Mean age in patients showing progressive, unaltered and regressive evolution was 46.4, 39.8 and 32.6 years, respectively, with a statistically significant difference between progressive and regressive evolution (p<0.05). It is suggested that high parasitemia did not have an influence on the evolution of the chronic infection.
Highlights
During 13 years, 190 individuals with chagasic infection were submitted to clinical and parasitological examinations to investigate the relationship between parasitemia and the evolution of chronic chagasic infection
Sabemos muito pouco sobre o alto parasitismo tecidual no chagásico crônico em vida
A informação disponível é a parasitemia que permite fazer conjecturas sobre sua importância na evolução clínica da doença
Summary
Estudou-se clínica e parasitologicamente, durante 13 anos, 190 indivíduos com infecção chagásica objetivando investigar a relação entre parasitemia e a evolução da doença de Chagas crônica. Estratificou-se a parasitemia em 1988/91, em alta, média e baixa e a correlação clínica mostrou que 5 (62,5%), 10 (41,7%) e 57 (36.1%) indivíduos, respectivamente, apresentaram evolução progressiva, sem diferença estatística significante, (p>0,05). Houve seis pacientes com alta parasitemia e, 59 sem parasitemia, verificado-se que 3 (50%) e 17 (28,8%), respectivamente, apresentaram evolução progressiva, sem diferença estatística significante, (p>0,05). As médias das idades daqueles com alta, média e baixa parasitemias foram 39,6; 45,3 e 41,5 anos, respectivamente, (p>0,05). As médias das idades dos pacientes com evolução progressiva, inalterada e regressiva foram respectivamente, 46,4; 39,8 e 32,6 anos, com diferença estatística significante entre aqueles com evolução progressiva e regressiva, (p
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Revista da Sociedade Brasileira de Medicina Tropical
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
