Abstract
To the Editor: We read with great interest the study by Philippa Lavallee et al1 in a recent issue of Stroke . The authors found in a case-control study of 450 subjects that the risk of stroke was significantly reduced in the subjects vaccinated against influenza during the last 5 years. The authors conclude that influenza vaccination may protect against brain infarction by reducing infections. A possible relationship between influenza and atherosclerosis, in particular myocardial infarction, was first suggested after epidemics of influenza struck Europe and the United States in the early 1900s.2 Increasing evidence exists indicating that inflammation and possibly infections play an important …
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