Abstract

A 32-year-old man underwent an F-18 fluordeoxyglucose positron emission tomography (FDG-PET/CT) scan for response assessment of mediastinal bulky non-Hodgkin lymphoma after completion of a CHOP therapy regimen. The F-18 FDG-PET/CT scan showed complete response regarding the mediastinal lesion. However, an unexpected pattern of prominent lung and abdominal muscular uptake was detected. The patient's clinical history was reassessed for differential diagnosis purposes. The medical records confirmed an episode of self-resolved influenza-like infection 4 days before the PET scan.This case underlines the importance of careful history taking before interpretation of PET scans. Viral infections should be included in the differential diagnosis of pulmonary diffuse F-18 FDG uptake.

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