Abstract
Aims: The aim of this study is documenting the presence of respiratory syncytial virus (RSV) and influenza virus infections in hospitalized patients with AE-COPD in autumn and winter months. Study Design: The study was designed as a prospective cohort study. Place and Duration of Study: September 2006 and February 2007, Izmir, Turkey. Methodology: Severe AE-COPD patients were studied by ready to use real time-PCR system and micro ELISA RSV and Influenza IGM and IgG antibody detection systems. Original Research Article Erbay et al.; BMRJ, 5(6): 459-465, 2015; Article no.BMRJ.2015.048 460 Results: Fifty AE-COPD cases enrolled to the study. Influenza and RSV were detected in 13 (26%) and 12 (24%) patients, respectively. Seven (14%) bacterial agents (4 P. aeruginosa, 2 S. pneumoniae, 1 E. coli) were isolated from patients with viral infections. Conclusion: Influenza viruses and RSV are important causative viral agents of AE-COPD. PCR and serological methods were decided to be used together for diagnosis of viral AE-COPD.
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