Abstract
1. Jennifer Cobelli Kett, MD 2. Anagha Loharikar, MD 1. Children's Hospital at Montefiore Bronx, NY Influenza. American Academy of Pediatrics. In: Pickering LK, Baker CJ, Long SS, McMillan JA, eds. Red Book: 2006 Report of the Committee on Infectious Diseases. 27th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 2006:401– 411 Parainfluenza. American Academy of Pediatrics. In: Pickering LK, Baker CJ, Long SS, McMillan JA, eds. Red Book: 2006 Report of the Committee on Infectious Diseases. 27th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 2006:479– 481 Prevention of Influenza: Recommendations for Influenza Immunization of Children, 2008–2009. American Academy of Pediatrics, Committee on Infectious Diseases. Pediatrics. 2008;122 :1135– 1141[OpenUrl][1][Abstract/FREE Full Text][2] Seasonal Influenza in Adults and Children–Diagnosis, Treatment, Chemoprophylaxis and Institutional Outbreak Management: Clinical Practice Guidelines of the Infectious Diseases Society of America. Harper SA, Bradley JS, Englund JA, et al. Clin Infect Dis. 2009;48 :1003– 1032[OpenUrl][3][Abstract/FREE Full Text][4] Seasonal Flu. Centers for Disease Control and Prevention. 2009. Available at: www.cdc.gov/flu Influenza is an orthomyxovirus, further classified into three types: A, B, and C. Types A and B are responsible for epidemic disease in humans. Influenza A viruses are categorized further based on surface antigens known as hemagglutinin (H) and neuraminidase (N). Current subtypes of influenza A viruses found in humans are H1N1 and H3N2. Frequent antigenic change, or antigenic drift , caused by point mutations during viral replication, results in new influenza virus variants, causing seasonal epidemics that generally occur in winter months in temperate zones. Occasionally, influenza A viruses undergo formation of an entirely new subtype through antigenic shift , resulting in a new hemagglutinin or neuraminidase protein, which creates the possibility of a pandemic. Rates of influenza infection are highest in school-age children during community outbreaks, which usually last 4 to 8 … [1]: {openurl}?query=rft.jtitle%253DPediatrics.%26rft_id%253Dinfo%253Adoi%252F10.1542%252Fpeds.2008-2449%26rft_id%253Dinfo%253Apmid%252F18779253%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=pediatrics&resid=122/5/1135&atom=%2Fpedsinreview%2F30%2F8%2F326.atom [3]: {openurl}?query=rft.jtitle%253DClin%2BInfect%2BDis.%26rft_id%253Dinfo%253Adoi%252F10.1086%252F598513%26rft_id%253Dinfo%253Apmid%252F19281331%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [4]: /lookup/ijlink?linkType=ABST&journalCode=cid&resid=48/8/1003&atom=%2Fpedsinreview%2F30%2F8%2F326.atom
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
