Abstract

A novel reassortant influenza A virus, H1avN2hu, has been found in Danish swine. The virus contains an H1 gene similar to the hemagglutinin (HA) gene of H1N1 avian-like swine viruses and an N2 gene most closely related to the neuraminidase (NA) gene of human H3N2 viruses from the mid-1990s.

Highlights

  • A novel reassortant influenza A virus, H1avN2hu, has been found in Danish swine

  • The influenza A viruses of the H1N1, H1N2, and H3N2 subtypes are enzootic in swine

  • A selection of positive samples were subtyped by partial sequencing of the HA and NA genes, which revealed the presence of a new reassortant influenza virus subtype in several of the submissions

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Summary

Introduction

A novel reassortant influenza A virus, H1avN2hu, has been found in Danish swine. The virus contains an H1 gene similar to the hemagglutinin (HA) gene of H1N1 avian-like swine viruses and an N2 gene most closely related to the neuraminidase (NA) gene of human H3N2 viruses from the mid-1990s. Influenza A viruses are important human and animal pathogens with high impacts on public and animal health. These viruses contain eight separate RNA segments, and the hemagglutinin (HA) and neuraminidase (NA) segments define the subtype.

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