Abstract
In 2016, a total of 18 human infections with influenza A(H3N2) virus occurred after exposure to influenza-infected swine at 7 agricultural fairs. Sixteen of these cases were the result of infection by a reassorted virus with increasing prevalence among US swine containing a hemagglutinin gene from 2010–11 human seasonal H3N2 strains.
Highlights
In 2016, a total of 18 human infections with influenza A(H3N2) virus occurred after exposure to influenza-infected swine at 7 agricultural fairs
We found that 7 fairs in Ohio (n = 4) and Michigan (n = 3) were associated with human H3N2v cases during July–August 2016
A fair-by-fair comparison of the influenza A virus genomes sequenced from human H3N2v cases and isolates from swine provided strong molecular evidence of zoonotic influenza A virus transmission
Summary
In 2016, a total of 18 human infections with influenza A(H3N2) virus occurred after exposure to influenza-infected swine at 7 agricultural fairs. 6 (fairs A–F) were participating in the active influenza A virus swine surveillance program. Illness among swine was reported at only 2 of the fairs (fairs A and E), suggesting that subclinical influenza A infections in pigs remain a threat to public health (3).
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