Influencing factors of nosocomial infection after operation in department of urology

Abstract

Objective To analyze the influencing factors of nosocomial infection after operation in the department of urology. Methods Between January 2014 and January 2017, 1587 patients who had undergone surgery in our hospital were included in the study. API assay system was used to identify the strains, and drug sensitive test was performed by disk diffusion method. The etiological distribution features of these strains were analyzed. Results Among the 1587 cases, 57 patients were infected, with an infection rate of 3.59%, 78 strains of pathogens were isolated through etiologic assay, of which, the numbers of pathogenic bacteria were the largest in the urinary system and reproductive system. The age of patients, the length of hospital stay, the complication of underlying diseases, and the uses of postoperative catheterization and antibiotics were found to be the risk factors of postoperative infection, the difference was statistically significant (P<0.05). Multiple logistic regression analysis showed that, the patients'age, the length of hospital stay, the complication of diabetes mellitus, antibiotics, and postoperative catheterization were the influencing factors of nosocomial infection (P<0.05). Among the 78 strains of pathogens isolated, 20 strains were gram positive bacteria, accounting for 25.64%, 51 strains of gram negative bacteria, accounting for 65.38%, 7 strains of fungi, accounting for 8.97%. Escherichia coli was the most common among the gram negative bacteria, and enterococcus faecalis among the gram positive bacteria. Through drug sensitive test, gram positive bacteria were found to be with relatively high drug resistance to penicillin G and levofloxacin, and low resistance to rifampin and vancomycin. Gram negative bacteria were with relatively strong sensibility to imipenem and macrodantin, and with relatively high resistance to cefazolin, ampicillin and gentamicin. Conclusions Gram negative bacteria is the main pathogens of nosocomial infection in patients in the department of urology after operation, and the pathogens have certain resistance to antibiotics. Therefore, drug sensitive test results should be followed strictly for medication, aseptic operation should be performed, and postoperative nutrition should be taken into account to improve the patients’ ability to fight infection and therefore reduce postoperative nosocomial infection. Key words: Urologic Surgical Procedures; Postoperative Complications; Infection