Abstract
Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni Mohammad Memorial Hospital. The data for the study were obtained from Hossana Queen Elleni Mohammad Memorial Hospital Antiretroviral Therapy clinic. The HIV infected patients ≥ 15 years of age. Binary logistic regression model was applied to analyze the data so as to identify the influencing factors associated with mortality of HIV infected patients. A total of 400 adult HIV infected patients who were under ART were included in the study. Of 400 patients, 18.75% of them died. Age of the patients 40 or above (OR=1.73, 95% CI: 1.13–1.92), primary education (OR=0.29, 95% CI: 0.030–0.71), secondary or above education (OR=0.13, 95% CI: 0.03–0.16), alcohol (OR=3.35, 95% CI: 1.79– 6.27), baseline weight 50 kg or above (OR=0.42, 95% CI: 0.23–0.77), TB positive (OR=3.76, 95% CI: 2.06–6.83), and baseline CD4 200 or above (OR=0.24, 95% CI: 0.19–0.50) were significantly associated with mortality among HIV patients under Antiretroviral Therapy. Health workers need to support those patients with no or little education by continuous awareness creation of taking care of themselves and knowing what factors facilitate death. Furthermore, patients who drink alcohol need to reduce excessive drinking.
Highlights
AIDS-related illnesses remain one of the leading causes of death globally and are projected to continue as a significant global cause of premature mortality in the coming decades [1]
A total of 400 adult HIV infected patients aged 15 years or Science Journal of Clinical Medicine 2021; 10(3): 72-77 older taking ART in Hosana Queen Elleni Mohamad Memorial Hospital were eligible for this study
The highest percentage of mortality of patients was observed for patients who were separated (40.0%) while it was lowest for patients who were married (14.3%)
Summary
AIDS-related illnesses remain one of the leading causes of death globally and are projected to continue as a significant global cause of premature mortality in the coming decades [1]. In 2011 about 34.2 million people were living with HIV/AIDS of which 30.7 million, 16.7 million and 3.4 million were adults, women and children younger than 15 years respectively. There were 1.7 million deaths due to AIDS of which about 230,000 were children younger than 15 years and rest of them were adults [2]. Sub-Saharan Africa has the most serious HIV and AIDS epidemic in the world. In 2010, about 68% of all people living with HIV resided in sub-Saharan Africa, a region with only. The epidemic continues to be most severe in southern Africa, with South Africa having more people living with HIV (an estimated 5.6 million) than any other country in the world. AIDS-related deaths have steadily decreased, as free antiretroviral therapy has become more widely available in the region. The total number of new HIV infections in sub-Saharan Africa has dropped by more than 26%, down to 1.9 million from the estimated 2.6 million at the height of the epidemic in 1997 [3]
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