Influencing factors of anxiety and depression in asthmatics

Abstract

To explore the major influencing factors for asthmatics with anxiety and depression. A total of 176 physician-diagnosed asthmatics were confirmed from March 2011 to March 2012 at First Affiliated Hospital of Zhengzhou University. And 144 were finally screened to examine their demographic characteristics and clinical features. Their status of anxiety and depression and the levels of control were evaluated with the scores of self-rating anxiety scale (SAS), self-rating depressive scale (SDS) and asthma control test (ACT). Firstly, asthma with anxiety and asthma with depression as a dependent variable, general demographics and clinical characteristics as independent variables, single-factor analysis revealed the relevant factors of asthma with anxiety and depression; secondly, multi-variable Logistic regression analysis was performed to examine the major influencing factors of anxiety and depression in asthmatics based on the relevant factors as independent variables. Multiple variables Logistic regression showed that residing place (rural vs city/town, OR = 0.28); control levels (partly controlled vs uncontrolled, OR = 0.22; control vs non-control, OR = 0.10); severity (secondary vs first level, OR = 1.42; third vs first level, OR = 2.32; forth vs first level, OR = 3.12) were the major influencing factors of anxiety (all P < 0.05). Meanwhile, age (31-45 vs ≤ 30 years, OR = 11.35; >45 vs ≤ 30 years, OR = 18.73); level of education (junior high vs primary school and below, OR = 3.30; high/secondary vs primary school and below, OR = 3.52; college and above vs primary school and below, OR = 3.60), medical history (1-3 years vs <1 year, OR = 2.68; >3 years vs <1 year, OR = 3.01); control levels (partial control vs uncontrolled, OR = 0.25; controlled vs uncontrol, OR = 0.18) were the major influencing factors of depression (all P < 0.05). Rural dwelling, poorly controlled and severe asthmatics are more likely to associate with anxiety. And depression moods are more common in those with an elder age, a long course of disease, higher education and poor control.