Influences of Hashimoto's Thyroiditis as Prognostic Factor of Papillary Thyroid Carcinoma

Abstract

Received November 4, 2013 Revised February 4, 2014 Accepted February 6, 2014 Address for correspondence Jong Chul Hong, MD, PhD Department of OtolaryngologyHead and Neck Surgery, Dong-A University College of Medicine, 26 Daesingongwon-ro, Seo-gu, Busan 602-715, Korea Tel +82-51-240-5428 Fax +82-51-253-0712 E-mail santa@dau.ac.kr Background and ObjectivesZZAs a prognostic factor, the association of Hashimoto’s thyroiditis (HT) with papillary thyroid carcinoma (PTC) is still controversial. The aim of this study is to compare clinicopathologic parameters between PTC alone and PTC with HT patients. Subjects and MethodZZWe reviewed the medical record retrospectively. 205 patients underwent thyroid surgery from January 2006 to December 2008. Among the 205 patients, 120 patients were included in this study. We compared various clinicopathologic parameters such as gender, tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, central lymph node metastasis, and lateral lymph node metastasis between PTC alone and PTC with HT patients. ResultsZZ18.3% of PTC patients were associated with HT. There were no significant differences in clinocopatholgic parameters such as gender, tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, central lymph node metastasis or lateral lymph node metastasis. Tumor recurrences were found in 6 out of 98 cases of PTC alone and in 3 out of 22 cases of PTC with HT. There was no significance between two groups (p=0.363). ConclusionZZResults indicate that HT may not be associated with clinicopathologic factors in PTC. Korean J Otorhinolaryngol-Head Neck Surg 2014;57(5):320-4