Abstract
Influence of Vitamin E on the Disposition Kinetics of Florfenicol after single and multiple oral administrations in Broiler Chickens
Highlights
Florfenicol is only used in veterinary medicine and has been approved by the Committee for Veterinary Medicinal Products
The aims of this study were to evaluate if vit E affects or change any of the pharmacokinetics of lorfenicol after single and multiple oral administration in broiler chickens at dose of 2 mg/kg b.wt. and 30 mg/kg b.wt
The work had been experimented on 12 broiler chickens with an average body weight from 1.280 to 2.00 kg and 45 days old, birds divided into four groups
Summary
Florfenicol is only used in veterinary medicine and has been approved by the Committee for Veterinary Medicinal Products (the European Agency for the Evaluation of Medical Products-EMEA). It is a potent agent used as an alternative to chloramphenicol. A particular drug may have no action on a targeted tissue whatsoever but may modify another drug’s in luence by varying its concentration available to produce an effect. This interaction may result either in diminished effects or drug potentiation [7].
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