Influence of viral infection in the murine orthotopic tracheal transplantation model in the development of Obliterative Airway Disease (OAD)

Abstract

chamber size, and a leftward shift of both systolic and diastolic force-length relationships. Computer-assisted volume reduction led to optimized ventricular reshaping and increased systolic force-length relationships (apex: 60 7%, middle: 70 9%, basis 64 8%, p 0.05). Thus, computer modelling allowed the optimization of preoperative planning and maximalizing force-length relationships intraopratively. Furthermore, free wall plication can be performed without cardiopulmonary bypass and thereby provides a less invasive approach for ventricular reconstruction.