Abstract
The intra-tumour blood flow distribution in two transplantable rat tumours was studied by isotope technique. Intravenous infusion of noradrenaline reduced significantly the blood flow distribution in both intramuscularly transplanted tumours and in normal muscle. This effect was counteracted by pre-treatment of animals with an alpha-receptor blocking agent, phenoxybenzamine. Tumour and muscle blood flows were moderately increased after ischaemia.
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