Influence of Tumor Characteristics on Early Surgical Complications in Operable Gastric Cancer

Abstract

Background: Gastric cancer is the 5th most common cause of cancer related death in Bangladesh. Curative resection remains the main modality of its successful treatment but the rate of postoperative complications is still high. Besides surgical factors, patient’s clinicopathological characteristics influence complications. Aims: To observe the nature of complications and correlate the tumor characteristics with nature of complications. Methods: Following convenience sampling 46 patients of operable gastric cancer who underwent gastrectomy in the Department of General Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), from July 2021 to June 2022 were observed for their postoperative complications rate, type, and grade by Clavien-Dindo classification system. Data were analyzed with Statistical Packages for Social Sciences (SPSS- 22.0) and Chi-square test (2) was done to find out the association of complications with the tumor characteristics. Results: Tumor located in fundus and corpus found in 10 cases, out of which 4(40.0%) and 6(60.0%) had developed major and minor complication respectively (p<0.05). Five 5 cases were adenocarcinoma (signet ring), among them 1(20.0%) developed major complication and 4(80.0%) developed minor complication. Five cases were adenocarcinoma (mucinous), 3(60.0%) developed major complication and 2(40.0%) developed minor complications (p<0.05). Grade III lesion was observed in 20 cases, out of which 5(25.0%) developed major complication and 15(75.0%) developed minor complications (p<0.05). Tumor size more than 6 cm was found in 3 cases, among them 1(33.3%) had major and 2(66.7%) had minor complication. Tumor size belonged to 3 - 6 cm was found in 34 cases, out of which 4(11.8%) had developed major complication, 28(81.4%) minor complication and 2(5.9%) had no complication (p<0.05). Tumor located in fundus and corpus, adenocarcinoma (signet ring), adenocarcinoma (mucinous), grade III lesion, tumor size 3 cm or more, .........