Abstract

The study aimed to evaluate the impact of thyroid dysfunction on serum electrolyte levels in individuals visiting outpatient departments of tertiary care institutes. The study included 88 participants who were divided into five groups: NTF, Hypo-TF, Hyper-TF, NTFT, and HC. The thyroid hormones T3, T4, and TSH and electrolyte levels, were analyzed in the sera obtained from the control and study groups. The results showed a statistically significant variation in thyroid hormone levels among the different study groups of both genders. The Hyper-TF group had higher levels of T3 and T4, while the TSH level was higher in the Hypo-TF group of both genders. The age of the patients and duration of treatment did not significantly affect the thyroid hormones and electrolyte levels of the study groups. The Na+ level was positively correlated with T3 and T4 levels of the control and Hypo-TF groups and TSH of the Hyper-TF group. The K+ level was negatively correlated with the thyroid hormone levels of each group except TSH of the Hyper-TF group. The study found that thyroid dysfunction significantly affected the thyroid hormone levels in male and female patients, which were positively correlated with Na+ level and negatively correlated with K+ level.

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