Abstract
Male, albino rats were treated with α-MSH, MSH/ACTH 4–10, MIF-I or a diluent control solution and then tested on a visual discrimination problem. Immediately after acquisition of the visual task the animals were tested with a spatial extradimensional shift problem. The animals treated with the MSH/ACTH 4–10 and MIF-I acquired the discrimination nonsignificantly faster than animals treated with α-MSH or a placebo. A subproblem analysis of the EDS behavior indicated that the peptides significantly improved performance probably by affecting attention.
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