Abstract
In 4 mongrel dogs with a Heidenhain pouch, selective gastric vagotomy, total gastrectomy, and an esophagoduodenostomy, the influence of vagotomy on inhibition of gastric secretion by fat in the duodenum was assessed. The amount of inhibition with the duodenum vagally innervated was not significantly different from the amount of inhibition when the duodenum was vagally denervated by truncal vagotomy. It is concluded that complete vagotomy does not interfere with the release of the inhibiting humoral substance released by fat in the duodenum.
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