Influence of the secondary ligand, phenanthroline, on the antioxidant and pro-oxidant and cytotoxic effects of the oxidovanadium(iv)/naringin complex

Abstract

Replacement of phen in [VO(Narg)2] induces greater π electronic delocalization, thus improving antioxidant action. However, due to its lipophilic character, cellular uptake of V is increased, leading to enhanced pro-oxidant and anticancer effects.