Abstract
Various fungi are known for their biological activities in men and thus are used as medicinal mushrooms. One of these, the basidiomycete Piptoporus betulinus (birch polypore), was already used by the ice man (Ötzi), probably as anti-inflammatory agent. Natural compounds and preparations of the fungus sole host genus – Betula species – are known for their activity in skin related disorders and are even discussed for their potency in cancer treatment. Triterpenoid compounds like betulin and betulinic acid are assigned to be responsible for these effects [1]. However, there is little knowledge on the natural compounds of the birch polypore and their potential skin protective properties. Therefore, the aim of this study was to investigate the activity of extracts of Piptoporus betulinus on a human keratinocyte cell line (HaCaT).
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