Abstract
To study the influence of HIV status on the occurrence of cervical precancerous lesions (CPL). This analytical cross-sectional study was carried out between 1st December 2019 and 31st May, 2020. All women with documented HIV status screened for CPL with biopsies done were recruited. The main variables recorded included maternal age, educational level, number of sexual partners, age at first sexual intercourse, smoking, alcohol consumption, HIV status, CD4 count, cervical biopsy result. Fisher exact test and t-test were used for comparison. P<0.05 was considered statistically significant. Concerning women attending our screening units, CPL was more frequent amongst those living with HIV/AIDS (20/92 or 21.7%) than among those not living with HIV/AIDS (29/290 or 10.0%) (P=0.004). As regards women living with HIV/AIDS, those with a CD4 count ˂350/ml were more at risk of having a CPL (OR 21.39, 95%CI 5.60-81.56, P ˂0.001). High grade lesions (CIN 2, CIN 3) were more found amongst women living with HIV/AIDS (OR 3.83, 95%CI 1.09-13.45, P=0.033). More attention should be paid to women living with HIV/AIDS, especially those with CD4 count ˂350/ml who should be screened more often with biopsy frequently conducted if indicated.
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