Influence of the degree of bacteriuria on perinatal results for asymptomatic urinary tract infection

Abstract

The objective: to conduct a comparative analysis of the outcomes of pregnancy, childbirth and the postpartum period in women with varying degrees of asymptomatic bacteriuria (AB) and to assess its role in the development of perinatal complications. Materials and methods. To identify the features of the course of childbirth and the postpartum period in BB, a comprehensive clinical study of 182 pregnant women was carried out, divided into 3 groups. Group I (main) included 85 pregnant women with asymptomatic bacteriuria >105 CFU/ml («severe» bacteriuria), group II included 52 pregnant women with АB 102–104 CFU/ml («moderate» bacteriuria) who did not receive treatment. Group III (control) consisted of 45 pregnant women without urinary tract infection. Statistical analysis of the research results was carried out using computer processing of the data obtained using the «Excell-5.0» and «Statistica» programs. Results. The age of the surveyed ranged from 16 to 42 years, while the average age was the same in the studied groups. In the first group it was 27.2±0.63 years, in the second group – 26.2±0.75 years, in the third (control) – 26.7±0.42 years. Premature birth was observed significantly more often in АB. Thus, pregnancy against the background of asymptomatic infection urinary tract ended in premature birth in 10.6% and 11.5% of observations in women of groups I and II, which did not exceed the general population indicator, however, in comparison with healthy patients, it increased in 4.8 and 5 times, respectively (p<0.05). Conclusion.The results of our study showed that АB affects the development of preterm labor, premature rupture of membranes, increases the frequency of pathological births, caesarean sections and pyoinflammatory diseases in the postpartum period. In pregnant women with asymptomatic infection urinary tract, regardless of the severity of bacteriuria, it is advisable to use antibiotic therapy to reduce intranatal and postnatal complications, reduce the severity and duration of recurrent infection urinary tract and reduce purulent-inflammatory diseases of puerperium.