Abstract
Obstructive coronary artery disease is a manifestation of ischemic heart disease, the most common cause of death in the world. At present, stents are used in more than 70% of percutaneous coronary interventions. A disadvantage of the technique is represented by in-stent restenosis, a common and difficult to treat re-narrowing of the artery [Gunn, 2002], which often occurs a few months after this intervention and may be linked to the local stress caused by the stent struts [Arjomand, 2003]. Evaluating the distribution and magnitude of stress within the vessel after stenting is important to study the stimuli for tissue growth. Stent-vessel interaction has been analyzed in literature, often using stent models with perfectly symmetric expansion. Uneven stent strut distribution has been observed in histological images from experimental animal models [Gunn, 2002]. This study considers the influence of uneven stent strut distribution in a coronary artery model.
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