Abstract
Frequency-based measures of heart rate variability have been shown to be a useful physiological marker in both clinical and research settings providing insight into the functioning of the autonomic nervous system. Ongoing interactions between the autonomic nervous system control of the heart and lung occurs during each ventilation cycle because of their anatomical position within the closed thoracic cavity. Mechanical ventilation and subsequent removal change the normal ventilator mechanics producing alterations in the tidal volume, intrathoracic pressure, and oxygen delivery. A noninvasive method called heart rate variability (HRV) can be used to evaluate this interaction during ventilation and can be quantified by applying frequency-based measures of the variability between heartbeats. Although HRV is a reliable method to measure alteration of the autonomic nervous system (ANS) function and cardiopulmonary interaction, there have been limited reports concerning the changes in the frequency-based measure of HRV during both spontaneous and mechanical ventilation. The purpose of this methodological study is therefore to describe the physiological influence of both spontaneous and mechanical ventilation on frequency-based measures of HRV.
Highlights
Heart rate variability (HRV) is a noninvasive method to evaluate the alteration of autonomic nervous system (ANS) function and cardiopulmonary interaction [1]
Respiratory parameters, including tidal volume (VT) and intrathoracic pressure (ITP), are the most common confounders seen among patients in intensive care units (ICUs) [10]
Patients with different modes of mechanical ventilation (MV) experience alteration in hemodynamic status and cardiovascular stability because of changes in ITP and Tidal volume (VT) [12]. This alteration might affect the ANS, which may be reflected by the frequencybased measure of HRV (RSA) [12]
Summary
Frequency-based measures of heart rate variability have been shown to be a useful physiological marker in both clinical and research settings providing insight into the functioning of the autonomic nervous system. A noninvasive method called heart rate variability (HRV) can be used to evaluate this interaction during ventilation and can be quantified by applying frequency-based measures of the variability between heartbeats. HRV is a reliable method to measure alteration of the autonomic nervous system (ANS) function and cardiopulmonary interaction, there have been limited reports concerning the changes in the frequency-based measure of HRV during both spontaneous and mechanical ventilation. E purpose of this methodological study is to describe the physiological influence of both spontaneous and mechanical ventilation on frequency-based measures of HRV HRV is a reliable method to measure alteration of the autonomic nervous system (ANS) function and cardiopulmonary interaction, there have been limited reports concerning the changes in the frequency-based measure of HRV during both spontaneous and mechanical ventilation. e purpose of this methodological study is to describe the physiological influence of both spontaneous and mechanical ventilation on frequency-based measures of HRV
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
