Abstract
This report examines postprandial renal calcium excretion (after shifts in daily calcium intake) in thyroid-intact (TI) and chronically thyroidectomized (TX) rats maintained on T4. Al l rats bore functional parathyroid transplants. The added effect of vitamin D deficiency (–D) was studied in rats placed on the – D diet shortly after weaning. In –D rats, 1,25-dihydrox-ycholecalciferol was undetectable in serum samples, while plasma calcium values remained normal. Bones of –D rats showed obvious signs of D deficiency after 4 months of the diet. Rats fed at 0800 h were trained to consume 10 g of their daily ration by 1 h, and urine was collected between 0930 and 1400 h, at which time an additional 6 g food were provided. The animals were followed for 10 days after a shift from low calcium intake t o daily intake of 160 mg calcium (1.0% diet) and on the first day of a calcium-free diet. The following results were obtained. 1) After transfer to a daily intake of 160 mg calcium, postprandial urinary calcium val...
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