Abstract

THE male is heavier than the female in the adults of most mammalian species. This trend is apparent at birth in humans1 and in many other mammals including the sheep, goat, cow, rat and monkey2. Little is known however, of the developmental basis for these birth weight differences. We have found that, one day before birth, male rat foetuses are 5% heavier than female foetuses, yet there seems to be no difference in the weights of their placentae.

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