Influence of selective serotonin reuptake inhibitors (SSRIs) in the development of bruxism

Abstract

ABSTRACT Objective To identify the relationship between the use of selective serotonin reuptake inhibitors (SSRIs) as pharmacological treatment and the development of bruxism. Methods A systematic literature search was performed in PubMed and Scopus databases, which included articles written within the last 30 years. The working hypothesis was that there is a significant association between using SSRIs as an antidepressant medication and developing bruxism. Results A total of four articles were included in the systematic review. All the articles are related to SSRI antidepressants and bruxism. Conclusion The results indicate that there is an apparent association between SSRI drug treatment and the development of bruxism. The methods of evaluation and analysis were different in each article and cannot be considered conclusive; however, there is sufficient information to elucidate the impact of SSRI drugs on the development of bruxism.