Abstract
Hydrazones derived from pyridoxal 5’‐phosphate and hydrazides of 2‐, 3‐, and 4‐pyridinecarboxylic acids protect the ascorbate from copper‐mediated oxidation in aqueous solution. • Hydrazones of PLP and pyridinecarboxylic acids hydrazides were synthesized. • Their stability and kinetics of formation were studied at pH 1.9; 6.6–7.4. • Their fluorescence and spectral properties are discussed. • Their ability to prevent copper-mediated ascorbate oxidation is evaluated.
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