Abstract
SummaryProtoveratrine was found to enhance the blood pressure responses to 1-norepinephrine and histamine in dogs and cats. This effect failed to occur in animals whose 9th and 10th nerves were sectioned bilaterally or whose spinal cord was transected. It is suggested that the hypotensive effect of protoveratrine is due to induced spontaneous or repetitive firing of baroceptors, which then become less susceptible to further stimulation or inhibition by changes of pressure.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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