Abstract
Glucose transport by uterine strips from ovariectomized estrogenized rats was explored. Sugar transport was significantly different from sacarose values (non-specific diffusion) only after 60 min of incubation. The addition of cytochalasin B demonstrated that we are measuring a specific mechanism for glucose transport. Insulin-enhanced sugar transport only at 0.5 or 0.25 U/ml prostaglandin E 1 (PGE 1), PGE 2 and PGF 2α (10 −7 M) significantly improved glucose transport, but indomethacin (10 −6 M) failed in modifying this parameter in either control nor insulin-treated tissues. We did not observe an additive or synergistic action between PGE 2 (10 −7 M) and insulin (used at maximal or submaximal concentration).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have