Abstract
The influence of polyethylene glycols on the response of rabbit erythrocytes to hemolytic concentrations of phenol, <i>m</i>-cresol, and <i>p</i>-chlorophenol has been determined. Through their interactions with each of these preservative agents, the polyethylene glycols were capable of preventing hemolysis. The higher molecular weight polymers were more effective complexing agents than those with lower degrees of polymerization. The ability of phenol and polyethylene glycols to interact was enhanced by the presence of sodium chloride. The hemolytic method represents a new approach in appraising phenolic–polyethylene glycol interactions and consequent preservative availability.
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