Influence of pituitrin and of adrenalin on the pupil of normal and ganglionectomized rabbits. A demonstration

Abstract

The impression prevails that adrenalin and pituitrin affect the body in the same direction. The most striking action is the production of a blood pressure rise by both substances. The action of both substances upon the uterus and upon the intestines are also in the same direction; the difference is only a quantitative one and it is slight. Several years ago one of us (M.) reported before this society that pituitrin acts strikingly different from adrenalin upon the pupil of rabbits on the side in which the superior cervical ganglion has been previously removed. We have recently studied the subject from various angles and wish to demonstrate the obtained results on these three rabbits. In two of these animals the superior cervical ganglion has been removed on one side several days ago; the third rabbit is a normal one. The demonstration shows the following facts. (1) The intravenous injection of pituitrin in a normal animal produces a considerable constriction of the pupil, while adrenalin produces a modera...