Abstract

Ever since the pioneer days of radiation therapy attempts have been made to influence the effects of irradiation by physical and chemical means in order to bring the desirable actions into the foreground and to eliminate or moderate the undesirable side effects. Our knowledge of the influence of physical procedures in this field, as, for example, the use of scattering media or the effects of temperature, is supported by a considerable number of careful experimental studies. In contrast, the many suggestions for the use of chemicals, hormones, and vitamins for influencing local or general effects of irradiation are based on a relatively small number of experimental studies. The majority of these suggestions depend on clinical observations, the results of which are frequently inconclusive and misleading. This is particularly true of the suggestions made for the treatment of the general intoxication of the irradiated body, clinically known as radiation sickness. Radiation sickness represents one of the major...

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