Abstract
Background: Argon plasma coagulation (APC) is used during bronchoscopy to restore passage of central airways. Concern has been raised about the possibility that elevated oxygen concentration may increase the tissue damage by APC. Objective: to examine the extent of tissue damage at different concentrations of oxygen in isolated pig tracheas. Methods: The APC-induced tissue damage was investigated macroscopically and microscopically in isolated and artificially ventilated pig tracheas at oxygen concentrations of 21, 50, 75 and 100%. Results: There was deep coagulation of all tissue layers reaching the adventitia independent of the oxygen concentration up to 75% O<sub>2</sub>. With 100% O<sub>2</sub>, only tissue damage increased and combustion occurred. Conclusions: APC-induced tissue damage in ex vivo pig tracheas was independent of the oxygen concentration relevant for clinical practice.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
