Abstract
Purpose To investigate the effect of OK lens treatment zone decentration on myopia control. Methods We retrospectively selected 30 OK lens wearers who met the following conditions in our hospital from more than 1300 cases: wearing lens in both eyes and only one eye was off-center while the other one was centric for more than 12 months. During the period of follow-up, the UCVA of each eye was better than 0.1 of logMAR and there were no obvious tropia, Kappa angle, and complications such as glare and diplopia. Result Among 30 cases, 15 are males and 15 are females, with an average age of 9.3 ± 1.51Y. There were no significant differences in equivalent spherical lens, astigmatism, e value, flat K, steep K, astigmatism, lens diameter, and toric between the two groups (p > 0.05). The average distance of decentration was 0.73 ± 0.25 mm. Axis growth per year in was 0.20 ± 0.24 mm the OK-lens-decentered group and 0.29 ± 0.20 mm in the OK-lens-centric group, which shows significant difference between them (p < 0.05). According to the direction of decentration, 30 decentered eyes were divided into temporal group (20 eyes) and other direction group (10 eyes). The efficiency of myopia control (the growth of AL per year in OK-lens-decentered eye/the growth of AL per year in the contralateral OK-lens-centric eye) was 0.69 ± 0.50 in the temporal decentration group and 0.75 ± 0.52 in the other direction group, showing no significant difference between them (p > 0.05). There was no significant correlation between the efficiency of myopia control and the degree of decentration among temporal decentration group (p > 0.05). Conclusion This self-control study without much interference factors shows that the decentration of OK lens can delay the development of myopia more effectively than being centric when uncorrected visual acuity was acceptable without obvious corneal complications, glare, or ghosting.
Highlights
Uncorrected refractive errors constitute the second major cause of vision loss of which myopia is the most common and well known [1, 2]
Orthokeratology is considered to be one of the most promising means of controlling the progress of myopia in children [12, 13]. e mechanism of myopia control is not completely clear, but it is generally believed that wearing OK lenses can reshape the anterior corneal surface, flatten the central cornea, steepen the paracentral cornea, change the image quality of the central and peripheral retina, and form the peripheral defocus [14, 15]
It will lead to errors caused by large individual differences if we use the axial length values directly when exploring the relationship between AL growth and direction or degree of decentration among different children, so we introduced the new variable named efficiency of myopia control (EMC), which shows how strong the effect of decentration on myopia control is in the same child
Summary
Uncorrected refractive errors constitute the second major cause of vision loss of which myopia is the most common and well known [1, 2]. Erefore, finding effective therapies to slow the progression of myopia could potentially benefit millions of individuals. Modern orthokeratology (OK) is a clinical nonsurgical method for temporary myopia correction and even controlling myopic progress in adolescents [5,6,7,8,9]. Orthokeratology is considered to be one of the most promising means of controlling the progress of myopia in children [12, 13]. E mechanism of myopia control is not completely clear, but it is generally believed that wearing OK lenses can reshape the anterior corneal surface, flatten the central cornea, steepen the paracentral cornea, change the image quality of the central and peripheral retina, and form the peripheral defocus [14, 15]. After orthokeratology, the center of the corneal optical area cannot be consistent with the pupil center in some patients
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