Influence of O025 ％ povidone iodine on ocular surface applied in conjunctival sac for cataract preoperative steriliztion

Abstract

Objective To observe the influence of 0.025％ povidone iodine (PI) on ocular surface after dropped in conjunctival sac for preoperative sterilization before cataract surgery.Methods Sixty cata ract patients (60 eyes) were treated by conjunctival sac sterilization for 30 seconds with 0.025％ povidone iodine 0.1 ml before cataract surgery.Lacrimal river height,corneal fluorescein staining,tear film break-up time (BUT),Schirmer's I test and conjunctiva impression cytology detection were observed on 3 d before surgery and 1 d,7 d,30 d postoperatively.A11 operations were phacoemulsification and intraocular lens implantation and performed by the same doctor.Then tobradex eye drops,sodium hyaluronate eye drops,pranoprofen eye drops were administered postoperatively.Results There was no statistical difference in lacrimal river height,Schirmer's I test,conjunctiva impression cytology detection between preoperative and postoperative.There was statistical difference about BUT among the 1 d,7 d postoperatively and preoperatively.There was statistical difference in corneal fluorescein staining scores between the 1 at day postoperatively and preoperatively.No statistical difference was detected after one week.There was no statistical difference on the 30th day.There was statistical difference in BUT between the 1 d,7 d postoperatively and preoperatively.There was no statistical difference after one month.There was statistical difference in corneal fluorescein staining scores between preoperative and postoperative 1st day,1st week and 1st month.Conclusion 0.025％ PIis safe for preoperative comjunctival sac sterilization for cataract patient.But the mean BUT reduced and corneal fluorescein staining increased on the postoperative early stage,the ocular surface recover in one month.The symptoms are more common in the patients with dry eye preoperatively,all of which recovered in one month. Key words: Povidone iodine; Conjunctival sac; Cataract; Ocular surface; Sterilize