Abstract
Non-thermal argon plasma needle at atmospheric pressure wasconstructed. The experimental setup was based on a simple and lowcost electric component that generates a sufficiently high electricfield at the electrodes to ionize the argon gas which flow atatmospheric pressure. A high AC power supply was used with 1.1kV and 19.57 kHz. Non-thermal Argon plasma used on bloodsamples to show the ability of non-thermal plasma to promote bloodcoagulation. Three tests have been done to show the ability of plasmato coagulate both normal and anti-coagulant blood. Each bloodsample has been treated for varying time from 20sec. to 180sec. atdifferent distances. The results of the current study showed that thecold plasma produced from argon significantly increase the in vitrospeed of blood coagulation, the plasma increases activation andaggregation of platelets, causes proliferation of fibroblasts and fibrinproduction accelerates blood coagulation.
Highlights
Over the past few years, nonthermal atmospheric pressure plasma has emerged as a novel promising tool in medicine
The results of the current study showed that the cold plasma produced from argon significantly increase the in vitro speed of blood coagulation, the plasma increases activation and aggregation of platelets, causes proliferation of fibroblasts and fibrin production accelerates blood coagulation
Sample preparation Blood samples were taken from healthy female donor. These samples were used to test the effect of laboratory made plasma needle system on blood coagulation, the effects of plasma needle were tested on both normal blood samples and anticoagulated blood samples, anticoagulated blood samples were tested in ethylene demine tetra acetic acid (EDTA) anti-coagulant tubes
Summary
Over the past few years, nonthermal atmospheric pressure plasma has emerged as a novel promising tool in medicine. As compared to the effects of the more conventional thermal plasma, non-thermal plasma is selective in its treatment since it does not burn tissue [1]. This enables many new medical applications, including sterilization of living tissue without damage [2], blood coagulation [2], induction of apoptosis in malignant tissues, and modulation of cell attachment [3,4]. All configurations the high voltage AC power supply generates high voltage of sinusoidal shape of 1.1kV (peak to peak) and frequency of 19.57 kHz
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