Abstract
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Highlights
Herpes-associated erythema multiforme is the most frequent form and occurs in 50-93% of patients with exudative erythema multiforme (EEM) [6, 8]
The trigger role of herpes simplex virus in the pathogenesis of EEM gives objective reasons to proscribe acyclic nucleosides to such patients [1, 2]
Because of what has been said, it appears important to study the connection between the immune system and the nervous system, and to search for new combined methods for adequate therapy to treat herpesassociated erythema multiforme, while taking into account the peculiarities of innate and adaptive functioning of the immune system
Summary
Herpes-associated erythema multiforme is the most frequent form and occurs in 50-93% of patients with exudative erythema multiforme (EEM) [6, 8]. The purpose of this study is to investigate the effect of the MNRI® therapeutic program on the innate and adaptive immune systems functions, and the peculiarity of cells cooperation in the immune response at the patients with HAEM. The failure of IFN-γ in the system of the observed patients showed a lower level in the serum with the reduction of induced production.
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