Abstract
Three strains of rats (Sprague-Dawley, Wistar-Kyoto and Wistar-Spontaneously Hypertensive) underwent unilateral section of the sciatic nerve. Some of the rats were exposed to chronic cold (4°C) and others were housed in normal temperature (22°C). Significant differences were found among the three strains in the frequency and severity of autotomy and stress-related pain behavior observed over a 12 week period. The rats that were the most prone to hypertension performed the least autotomy. Common mechanisms involved in the control of blood pressure and pain may underly these observations.
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